Journal club

DatePresenterTitle/ about 15 minutes, < 20 minutes
24-03-20251.YangNSGeneious prime usage
31-03-20252. ChenX1. Active in vivo translocation of the Methanosarcina mazei Gö1 Casposon. Nucleic Acids Res. 2023
2. Casposase structure and the mechanistic link between DNA transposition and spacer acquisition by CRISPR-Cas eLife 9:e50004.
07-04-20253. AddyTransposition of Mutator-like transposable elements (MULEs) resembles hAT and Transib elements and V(D)J recombination-2017-NAR
21-04-20254. WijdanA Naturally Active Spy Transposon Discovered from the Insect Genome of Colletes gigas as a Promising Novel Gene Transfer Tool-2024-ADS
28-04-20255. AhmedCharacterizing Mobile Element Insertions in 5,675 Genomes
6-5-20256. XXxingAll-RNA-mediated targeted gene integration in
mammalian cells with rationally engineered R2 retrotransposons-cell
19-05-20257. XianKLCas9-induced targeted integration of large DNA payloads in primary human T cells via homology-mediated end-joining DNA repair-2024-nbe
2-6-20258. LiMYTransposase-assisted target-site integration for efficient plant genome engineering-2024-nature
9-06-20259. WanQTransposase N-terminal phosphorylation and asymmetric transposon ends inhibit piggyBac transposition in mammalian cells-NAR-2022
16-06-20251. PhiriGenomic Analysis Revealed a Convergent Evolution of LINE-1 in Coat Color_ A Case Study in Water Buffaloes (Bubalus bubalis)-MBE-2021
23-06-20252. XinChenMegabase-scale human genome rearrangement with
programmable bridge recombinases-2025-preprint
30-06-20253. AddyFunctional characterization of the active Mutator- like transposable element, Muta1 from the mosquito Aedes aegypti-mobile DNA-2017
July-74. XianKLProtein Mutational Effect Predictor (ProMEP)
Zero-shot prediction of mutation effects with multimodal deep representation learning guides protein engineering
July-145. AhmedAn Alu insertion map of the Indian population: identification and analysis in 1021 genomes of the IndiGen project. NAR Genom Bioinform. 2022
July-216. XXxing2025-nature-Reprogramming site-specific retrotransposon activity to new DNA sites
July-307. WijdanTransposase expression, element abundance, element size, and DNA repair determine the mobility and heritability of PIF-Pong-Harbinger transposable elements-2023-front-cell-and-biology
8. LiMYDiscovery and structural mechanism of DNA endonucleases guided by RAGATH-18-derived RNAs-2024
9. WanQA programmable seekRNA guides target selection by IS1111 and IS110 type insertion sequences
10. NSYang
PPT in English and Chinese, talk less than 15 minutes in Eng.