Distribution of TEs across the eukaryote phylogeny
转座子分布和结构
生物进化分类
科普视频
TE keynote lectures
*Part 1: Introduction to transposable elements (38 minutes) by Susan Wessler
*Part 2: How transposable elements amplify throughout genomes (70 minutes) by Susan Wessler
*Transposable Element-mediated Structural Variation: From McClintock to Pangenomes – YouTube by Susan Wessler, department of Botany and Plant Sciences, University of California (55 minutes)
The Dynamic Genome: Unintelligent Design – YouTube by Susan Wessler department of Botany and Plant Sciences, University of California (60 minutes)
LINE1 by Haig Kazazian Jr – YouTube 43′
CARTA: Comparative Anthropogeny – LINE1 Retrotransposons – YouTube 21′
* Understanding the Strategies Evolved by a Very Successful Transposable Element by Dr. Susan Wessler – YouTube department of Botany and Plant Sciences, University of California 80 minutes
*All roads lead to transposons: Dr. Cedric Feschotte, Cornell UniversityCornell University – YouTube (38 minutes)
*Transposon site-specificity and genome evolution – Allan Spradling – YouTube (50 minutes)
*EMBL Keynote Lecture – Germline reprogramming and epigenetic inheritance of transposable elements – YouTube Robert Martienssen, Cold Spring Harbor Laboratory, USA (68 minutes)
*Transposable elements, DNA methylation and transgenerational epigenetics, lessons from plants – YouTube Vincent Colot – Institut de Biologie de l’École Normale Supérieure (IBENS) – CNRS (58 munutes)
*Jumping Genes Lead the Way – YouTube by Uwe Hilgert, DNA learning center, University of Arizona (60 minutes)
*LINE impact: CGC Webinar Series – June 2021 – YouTube 58 minutes
Vir_S14_L15 Retroviruses – YouTube 64′
*Unit8C Transposable Elements – YouTube, 20 minutes
CSHL Keynote Series, Junk Evolution: Dr Andrew Clark, Cornell University – YouTube 54 minutes
*Retroelements: YouTube (85minutes)
Chemistry of Life Part – YouTube 43 minutes
Lecture 1 (2021) How transposable elements amplify throughput genomes by Ruslan Kalendar, plants, University of Helsinki (40 minutes)
Barbara McClintock’s Controlling Elements, Then and Now – YouTube (60 minutes)
Machine Learning in Bioinformatics: Understanding Transposable Elements – YouTube (20 minutes)
Accelerated Evolution by Diversity-Generating Retroelements – Jeff Miller – YouTube (28 minutes)
The Jumping Genome: Changing Ideas about Heredity and Evolution – YouTube (75 minutes)
*CSHL Keynote, Retrotransposon storm hypothesis of ALS—The dangers of a Collyer’s genome Dr. Josh Dubnau, Stony Brook School of Medicine – YouTube (40minutes)
TEHUB
TEHUB // dnaPipeTE Demo by Clément Goubert // Uppsala 2022 – YouTube 30 minutes
TEHUB // Introduction to TE-hub // Uppsala 2022 – YouTube 20 minutes
TE-hub – YouTube 20 minutes
TEHUB // DFAM Demo by Jessica Storer // Uppsala 2022 – YouTube 34 minutes
TEHUB // RepeatMasker Demo by Jessica Storer // Uppsala 2022 – YouTube 34 minutes
TEHUB // ECCsplorer by Ludwig Mann // Uppsala 2022 – YouTube 30 minutes
TEHUB // REPET demo by Johann Confais // Uppsala 2022 – YouTube 20 minutes
TEHUB // RepeatExplorer Demo by Petr Novák // Uppsala 2022 – YouTube 30 minutes
TE lectures
DNA Interest Group Event: Transposable Elements- The “Ghosts” in Our DNA – YouTube (52 minutes)
EMBL Keynote Lecture – The Nucleosome: Guardian and Gateway to Genomes – YouTube (60 minutes)
SEEM 2022 01 14 Yann Bourgeois: “Studying the population dynamics of transposable elements” – YouTube (50minutes)
Transposable element activation in Alzheimer’s disease and related tauopathies │Dr Bess Frost – YouTube (60 minutes)
How Can Transposons Accelerate Your Genomics Research? (50 minutes)
Unit8C Transposable Elements – YouTube (20 minutes)
CGM79期:区树俊 Bench-marking transposable element annotation methods – YouTube (中文，48minutes)
Lee Kass – “Barbara McClintock at Cornell university: 1919-1939 & Beyond” – YouTube (50 minutes)
*Your Genomic Parasites – YouTube (45 minutes)
Transposons / Transposable elements explained (20 minutes)
Introduction to Transposons (7 minutes) by Nicole Lantz
Plasmids and Transposons (26 minutes)
DNA Tn
piggyBac Transposons to Cut and Paste DNA (28 minutes) by Lauren E. Wooddard
PiggyBac Applications: Beyond Stable Cell Lines – YouTube （20 minutes）
DNA Transposons (13 minutes)
TcBuster (TM) (1.38 minutes) by Bio-Techne company
Faculty Talk Series | Prof. Zoltan Ivics – YouTube 60 minutes
ESGCT e-School: The Sleeping Beauty transposon – a molecular parasite tamed for genome engineering – YouTube (56 minutes)
RTn
Role of transposons in brain and learning processes | Dr. Peter Borger | EN – YouTube (55 minutes)
Daniel Caffrey – Evolution of Alu elements in long non coding RNA and mRNA – YouTube (45 minutes)
CARTA: Comparative Anthropogeny – LINE1 Retrotransposons – YouTube (21 minutes)
Lec 2.8.1 Alu Transposon – YouTube (20 minutes)
RNA Transposons (15 minutes)
TE repression
Linquist and Fullerton – Epigenetics and Transposon Dynamics – DS² 2021 – YouTube (45 minutes)
Zamudio N (2015): Loss of DNA methylation at transposons alters chromatin landscape… – YouTube (50minutes)
Epigenetic Repression of Transposons by an RNA-based Innate Immune System – Greg Hannon – YouTube 60 minutes
Gene editing
2025年7月11日The Scientist Symposium: The Future of CRISPR – YouTube
2025年5月4日: The Future of Genetic Engineering. #sciencedocumentary
2025年7月16日: CTSI Distinguished Speaker Series | Patrick Hsu
2024年11月26日Unlocking CRISPR Advances in Base Editing, Prime Editing and Future Applications
2024年11月12日Advanced solutions for CRISPR gene editing
2024年2月4日: The Rise Of Genetic Engineering | Gene-Editing Technology | Science Documentary
2024年7月13日: “Bridge RNAs direct programmable recombination of target and donor DNA” – YouTube
2024年11月10日CRISPR KO vs CRISPR KI experiment using CRISPR-Cas9
2024年4月18日Jennifer Doudna: The Future of CRISPR: What’s Ahead for Genome Editing
2024年11月20日：How to optimize non-viral CRISPR HDR for high-efficiency large knock-in in primary T cells and iPSCs*
2024年10月16日 Boost CRISPR Editing Efficiency Using Optimized sgRNA and HDR Template Design
2024年8月26日CPHR Seminar Series – David Liu
2023年11月17日David Liu: Base Editing and Prime Editing (Correcting Mutations that Cause Genetic Disease)
2023年12月14日Enabling GMP Production of sgRNA for CRISPR-Based Cell and Gene Therapies
2023年12月2日：Leveraging Programmable CRISPR-Associated Transposases for Next-Generation Genome Engineering
2023年10月26日Unveiling the potential of CRISPR: A guide to gene editing
2023年9月14日: From CRISPR-Cas to Tas (transposon-associated proteins) – Professor Virginijus Šikšnys
2023年6月17日: Discovery and development of CRISPR-associated transposases for next-generation genome engineering
2023年11月30日Jennifer Doudna: Clare Hall King Lecture 2023 – Jennifer Doudna
2022年12月16日Base editing in practice – YouTube
2022年3月22日 An improved solution for generating large CRISPR HDR knock-ins*
2021年5月28日2021 Edward Novitski Prize: Feng Zhang
2020年4月17日Alt-R HDR Design Tool & Templates
2020年8月18日Base Editing: Putting Precision into Genomic Medicine – YouTube
2020年2月25日： A Workflow for Knock-in Genome Editing: Simplified
2020-2: GENE EDITING EXPLAINED! – A comprehensive guide to the principles, methods and technologies!
2020年12月1日Novel CRISPR Knock-In Technology for the Robust Analysis of Cells and Tissue
2018-3：How to use CRISPR Cas9 for knockout, knock in and gene activation
2018年10月15日Webinar: Strategies to Efficiently Generate CRISPR KO/KI Cell Lines
*2017年3月17日：Getting started with CRISPR: a review of gene knockout and homology-directed repair
Jennifer Doudna: Jennifer Doudna: CRISPR Basics
Feng Zhang 2017: From microbial immunity to genome editing – YouTube (60 minutes)
Targeted DNA integration without double strand breaks using CRISPR RNA guided transposons – YouTube 30′
How does Retroelement DNA Writing work, and what is DNA imaging? – YouTube 90 minutes
Stanford Webinar – CRISPR – 10 Years of Genome Editing and More – (60 minutes)
2022 FUTURES Gene Therapy and Gene Editing Symposium Brunch – YouTube (80 minutes)
CMB Journal Club: Genome Editing – YouTube, 21 minutes
Saturation Genome Editing in RAD51C – YouTube 24 minutes
Scientist Stories: George Church, The Future of the Genome Editing Revolution – YouTube 80 minutes
*MIT: Rewriting DNA: Big Returns from Gene Editing – YouTube 83
Basic Principles of Genome Editing – YouTube 84
Lec 10: Basics of Zinc Finger Nucleases – YouTube, 51′
MIT CompBio Lecture 24 – Genome Engineering – YouTube, 80′
Zinc fingers: From gene switches to gene therapy – YouTube, 76
Engineered zinc finger proteins (ZFPs) for the regulation of gene expression – YouTube 68
Giving Evolutionary Biologists the (Zinc) Finger – YouTube 80
Genome Editing with Engineered Zinc Finger Proteins – Philip D. Gregory – YouTube 40
Genome Editing – Shawn Burgess – YouTube 40
Lecture 7 Leucine Zipper motifs – YouTube 23
Gene therapy
2024年1月28日CAR-T Cell Therapy: A New Chapter in Lupus Treatment? – YouTube
2024年10月30日Lupus Ontario Symposium 2024 – CAR T-Cell Therapy and Upcoming Treatments
2024年11月12日CAR T-cell Therapy: An Emerging Therapy in Autoimmune Diseases
2023年8月1日Gene-editing Technologies: Powerful Tools Rewriting the Code of Life
2023年12月5日How to Create CRISPR-Edited T Cells More Efficiently for Tomorrow’s Cell Therapies
2022年2月8日 ESGCT e-Seminar: Virus-free gene editing of T cells
2021年5月1日Updates in CAR T Cell Therapies
2021年7月29日CRISPR/Cas9-based genome editing for autologous CAR-T cell production
2020年12月16日ESGCT e-School: Cancer immunotherapy: beyond CAR T cells
2020年5月6日ESGCT e-School: Gene Therapy – From Concept to Proof
2020年7月22日ESGCT e-School: Knock-out, Knock-in, repair or regulate – the tool-box of designer nucleases
2020年7月29日ESGCT e-School: Nucleases used for gene editing
2020年6月10日ESGCT e-School: The Sleeping Beauty transposon – a molecular parasite tamed for genome engineering
2021年2月10日Toni Cathomen, University of FreiburgESGCT e-Seminars: Safety considerations in therapeutic genome editing
2021年2月17日ESGCT e-Seminars: Intellia’s Modular CRISPR/Cas9 Gene Editing Platform for the Treatment of Disease
2020年5月6日ESGCT e-School: Gene Therapy – From Concept to Proof – YouTube
2020年6月16日 A CRISPR Vision for the Future of Cell Therapy
Gene Therapy (60 minutes)
ESGCT 2017 Education Day – Zsuzsanna Izsvak – YouTube 30 minutes
Evolution of AAV Vector for Gene Therapy – YouTube (30 minutes)
April 2022 Cure SMA and Novartis Gene Therapies Clinical Trial Update Webinar – YouTube (45 minutes)
Gene Therapy Yesterday, Today and Tomorrow (60 minutes)
The Science Behind Gene Therapy – (60 minutes)
Gene Therapy: Getting Up to Speed (40 minutes)
Cancer Gene Therapy 2.0: Immunotherapy for Cancer （60 minutes）
Gene Therapy Manufacturing Workshop –(60 minutes)
Manufacturing of Cell-Based Therapies – (50 minutes)
New Innovations in Cell Therapy – (80 minutes)
Gene Therapy Explained (4.30 minutes) by AGTC company
Gene Therapy Basics (4 minutes)
The Basics of Gene Therapy – (5 minutes) by Roche
Gene therapy is the future of medicine (10 minutes) by Dr. Nafiseh Nafissi
2022 WMIF: Non-viral Vectors for Gene Therapy (60 minutes)
Nanoparticle Gene Delivery (1.28 minutes) by Johns Hopkins Institute
The history of the cell, cell therapy, gene therapy, and more (120 minutes)
From the Human Genome Project to Precision Medicine: A Journey to Advance Human Health – Eric Green – YouTube (100 minutes)
Benchling Webinar: Codon Optimization (50 minutes)
Prof. Katalin Karikó「Developing mRNA for therapy」 – YouTube 32′
CAR-T/CAR-NK
https: First Child To Receive CAR T-Cell Therapy Is 10 Years Cancer-Free
the Emily Whitehead Foundation：https://www.youtube.com
The girl whose T cells beat cancer： https://www.youtube.com
Non-viral Vectors for Gene Therapy: https://www.youtube.com 60
Non-Viral Vectors: https://www.youtube.com 50
https://www.youtube.com/watch?v=U7Tk8BfIcpg
Cutting Edge Viral and Non-Viral Delivery Platforms for T-Cell Engineering and Beyondhttps://www.youtube.com44
New viral and non viral platforms for T cell engineeringhttps://www.youtube.com57
A cGMP Compatible, Non-Viral CAR T Cell Manufacturing Process – YouTube 60 minutes
Non-viral T cell engineering for clinical manufacturing [WEBINAR] – YouTube 60 minutes
https://www.youtube.com/watch?v=Odvi5prOAX8 24
CAR T-Cell Therapy | FAQ with Dr. Patrick Brown (10 minutes)
A 2023 Update on CAR-T Therapy in Myeloma with Dr. Craig Hofmeister – YouTube 63′
CAR T-cell Therapy: The Good, The Bad and The Long-Term 2022 – YouTube 60′
CAR T Immunotherapies-Engineering Cell Fitness: TET2-disrupted CAR T cells – YouTube 28′
New treatment horizon : Chimeric Antigen Receptor CAR T Cell Therapy – YouTube 66′
Therapeutic T cell engineering: CD19 CAR therapy and beyond, Center for Cell Engineering, NY 40′
Science Spotlight – CAR T Cells: On the Road to Synthetic Immunity | Memorial Sloan Kettering 62′
CAR T-cell Therapy in Multiple Myeloma 52′
Understanding CAR T-cell therapy (November 2020) 68
Immuno Oncology Scientific Updates Webcast Tumor Mutational Burden 52
Update on CAR T Cell Therapy for Diffuse Large B-Cell Lymphoma | LRF Webinars 62
A CRISPR Vision for the Future of Cell Therapy 68
Targeting Cancer Pathways: Understanding Immune Checkpoints 60
CD19 CAR T Cell Therapy for Pediatric ALL: The Seattle Children’s Experience 57
Chimeric Antigen Receptors: From proof of concept to widely applicable clinical research solutions 52
CAR T Cell Webinar 28 November 2017 62
Structure-Function Relationship in Chimeric Antigen Receptors – Maksim Mamonkin 30
Simplifying GMP CAR T and CAR NK cell therapy manufacturing processes [WEBINAR] – YouTube 64
Webinar – CAR-T Approval: What’s Next? – YouTube 61
Session 1: Overview of T-cell therapies – current status – YouTube 120
Genome
CGC Webinar – March 2023 – YouTube 60
DNA damage: Dr Stephen J Elledge – YouTube 38′
Complete ChatGPT Tutorial – [Become A Power User in 30 Minutes] – YouTube, 30 minutes
Genome: Unlocking Life’s Code – YouTube, 120 minutes
6.047/6.878 Lecture 18 – Genome Evolution (Fall 2020) – YouTube 90 minutes
CARTA: The Evolution of Human Biodiversity: Evan Eichler -Genome Structural Variation – YouTube 30 minutes
CRISPR Biology and the New Era of Genome Engineering – YouTube 90 minutes
Regulatory and Epigenetic Landscapes of Mammalian Genomes – Laura Elnitski (2012) – YouTube 73 minutes
Sergey Koren: A Complete Diploid Human Genome – YouTube 60 minutes
Bjorn Schumacher, Genome Stability in Aging and disease – YouTube , 26 minutes
Human Genome Project & The DNA Molecule Explained – YouTube 42 minutes
How Genome Size Constrains Plant Ecology and Distribution | Andrew Leitch – YouTube 70 minutes
Molecular biology and Techniques
Molecular Biology #1 2020 – YouTube 90′
Molecular Biology #2 2020 – YouTube 68′
Molecular Biology #3 2020 – YouTube 90′
Molecular Biology #4 2020 – YouTube 90′
Molecular Biology Techniques – YouTube 200′
BioM01 Molecular Biology 2021 2022 Structure of nucleic acids – YouTube 72′
MED LEVEL 1 GEN BIO Lecture of Molecular Biology techniques 1,MTI 2022 – YouTube 26′
Basic Molecular Biology Research Techniques – YouTube 68′
Molecular Biology Techniques – YouTube 71′
Experimental Techniques in Molecular Biology, Part I – YouTube 56′
Epigenetics
Science on the Grand 2019 Keynote: Epigenetics and Future Scientists – YouTube 37′
Trauma’s Effect on the Lifecourse: An overview of epigenetics – YouTube 51′
Keynote: How Chromatin organization and epigenetics talk with… – Gil Ast – ISMB/ECCB 2013 – YouTube 57′
What is epigenetic and why knowing it will change your life ? – Dr Moshe Szyf – YouTube 60′
Epigenetic inheritance – health and lifestyle across the generations – YouTube 52′
Genomic Imprinting and Mammalian Evolution | Azim Surani, Gurdon Institute Cambridge, UK – YouTube 63′
Karin B. Michels | Is Epigenetics Inherited? || Radcliffe Institute – YouTube 44′
What is Epigenetics? – with Nessa Carey – YouTube 40′
Howard Chang (Stanford, HHMI) 1: Epigenomic Technologies – YouTube 40′
Howard Chang (Stanford, HHMI) 2: LncRNA Function at the RNA Level: Xist – YouTube 24′
Howard Chang (Stanford, HHMI) 3: LncRNA Function at the DNA Level: PVT1 – YouTube 23′
C. David Allis (Rockefeller U.) 1: Epigenetics: Why Your DNA Isn’t Enough – YouTube 42′
C. David Allis (Rockefeller U.) 2: Epigenetics in Development and Disease – YouTube 45′